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Tuğba-Kartal and Çağla-Mutlu (2020) also demonstrated in a retrospective review of 129 paediatric patients that a treatment regimen of sublingual B12 (both CN-Cbl and methyl-Cbl) at 1 mg once daily for 7 days then every other day for 3 weeks was as effective as the same dose schedule of IM B12 at normalising serum B12 levels

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55 Increased iron load and toxicity has also been implicated in ferroptosis, a regulated cell death mechanism caused by the accumulation of lipid peroxidation products